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Effects of growth hormone on cardiac remodeling and soleus muscle in rats with aortic stenosis-induced heart failure

BACKGROUND: Skeletal muscle wasting is often observed in heart failure (HF). The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis is impaired in HF. In this study, we evaluated the effects of GH on soleus muscle and cardiac remodeling in rats with aortic stenosis (AS)-induced HF. METHOD...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Lima, Aline R.R., Pagan, Luana U., Damatto, Ricardo L., Cezar, Marcelo D.M., Bonomo, Camila, Gomes, Mariana J., Martinez, Paula F., Guizoni, Daniele M., Campos, Dijon H.S., Damatto, Felipe C., Okoshi, Katashi, Okoshi, Marina P.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669945/
https://ncbi.nlm.nih.gov/pubmed/29137319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20583
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