Hic-5 regulates epithelial to mesenchymal transition in ovarian cancer cells in a TGFβ1-independent manner

The molecular basis of epithelial ovarian cancer (EOC) dissemination is still poorly understood. We have previously identified the hydrogen peroxide-inducible clone-5 (Hic-5) gene as hypomethylated in high-grade (HG) serous EOC tumors, compared to normal ovarian tissues. Hic-5 is a focal adhesion sc...

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Udgivet i:Oncotarget
Main Authors: Sheta, Razan, Wang, Zhi-Qiang, Bachvarova, Magdalena, Plante, Marie, Gregoire, Jean, Renaud, Marie-Claude, Sebastianelli, Alexandra, Gobeil, Stephane, Morin, Chantale, Macdonald, Elizabeth, Vanderhyden, Barbara, Bachvarov, Dimcho
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669907/
https://ncbi.nlm.nih.gov/pubmed/29137281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19714
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