An oral keratinocyte life cycle model identifies novel host genome regulation by human papillomavirus 16 relevant to HPV positive head and neck cancer

Many aspects of the HPV life cycle have been characterized in cervical cell lines (W12, CIN612) and in HPV immortalized primary foreskin keratinocytes. There is now an epidemic of HPV positive oropharyngeal cancers (HPV16 is responsible for 80-90% of these); therefore increased understanding of the...

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Publicado en:Oncotarget
Autores principales: Evans, Michael R., James, Claire D., Loughran, Oonagh, Nulton, Tara J., Wang, Xu, Bristol, Molly L., Windle, Brad, Morgan, Iain M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669857/
https://ncbi.nlm.nih.gov/pubmed/29137231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18328
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