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Intra-hepatic Depletion of Mucosal Associated Invariant T cells in Hepatitis C Virus-induced Liver Inflammation

BACKGROUND & AIMS: Chronic hepatitis affects phenotypes of innate and adaptive immune cells. Mucosal associated invariant T (MAIT) cells are enriched in the liver as compared to the blood, respond to intra-hepatic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated f...

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Publicado en:Gastroenterology
Main Authors: Bolte, Fabian J., O’Keefe, Ashley C., Webb, Lauren M., Serti, Elisavet, Rivera, Elenita, Liang, T. Jake, Ghany, Marc, Rehermann, Barbara
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669813/
https://ncbi.nlm.nih.gov/pubmed/28780074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2017.07.043
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