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Severe eosinophilic asthma: from the pathogenic role of interleukin-5 to the therapeutic action of mepolizumab

Mepolizumab is an anti-interleukin-5 (IL-5) humanized monoclonal antibody that has been recently approved as an add-on biological treatment for severe eosinophilic asthma, by both the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). Moreover, mepolizumab is also current...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Pelaia, Corrado, Vatrella, Alessandro, Busceti, Maria Teresa, Gallelli, Luca, Terracciano, Rosa, Savino, Rocco, Pelaia, Girolamo
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669784/
https://ncbi.nlm.nih.gov/pubmed/29133975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S150656
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