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Prediction of HIV-1 sensitivity to broadly neutralizing antibodies shows a trend towards resistance over time

Treatment with broadly neutralizing antibodies (bNAbs) has proven effective against HIV-1 infections in humanized mice, non-human primates, and humans. Due to the high mutation rate of HIV-1, resistance testing of the patient’s viral strains to the bNAbs is still inevitable. So far, bNAb resistance...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Hake, Anna, Pfeifer, Nico
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669501/
https://ncbi.nlm.nih.gov/pubmed/29065122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005789
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