Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations

Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression. The identification of the functional relevance of individual fibrinogen single nucleotide polymorphisms (SNPs) has been hindered by...

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Pubblicato in:PLoS One
Autori principali: Cronjé, H. Toinét, Nienaber-Rousseau, Cornelie, Zandberg, Lizelle, de Lange, Zelda, Green, Fiona R., Pieters, Marlien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669433/
https://ncbi.nlm.nih.gov/pubmed/29099861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187712
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