Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations

Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression. The identification of the functional relevance of individual fibrinogen single nucleotide polymorphisms (SNPs) has been hindered by...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Cronjé, H. Toinét, Nienaber-Rousseau, Cornelie, Zandberg, Lizelle, de Lange, Zelda, Green, Fiona R., Pieters, Marlien
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669433/
https://ncbi.nlm.nih.gov/pubmed/29099861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187712
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