1-Amino-4-hydroxy-9,10-anthraquinone – An analogue of anthracycline anticancer drugs, interacts with DNA and induces apoptosis in human MDA-MB-231 breast adinocarcinoma cells: Evaluation of structure–activity relationship using computational, spectroscopic and biochemical studies

The X-ray diffraction and spectroscopic properties of 1-amino-4-hydroxy-9,10-anthraquinone (1-AHAQ), a simple analogue of anthracycline chemotherapeutic drugs were studied by adopting experimental and computational methods. The optimized geometrical parameters obtained from computational methods wer...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Mondal, Palash, Roy, Sanjay, Loganathan, Gayathri, Mandal, Bitapi, Dharumadurai, Dhanasekaran, Akbarsha, Mohammad A., Sengupta, Partha Sarathi, Chattopadhyay, Shouvik, Guin, Partha Sarathi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669404/
https://ncbi.nlm.nih.gov/pubmed/29124219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.10.008
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