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Salbutamol inhibits ubiquitin-mediated survival motor neuron protein degradation in spinal muscular atrophy cells

Spinal muscular atrophy (SMA) is a common autosomal recessive neuromuscular disorder that is currently incurable. SMA is caused by decreased levels of the survival motor neuron protein (SMN), as a result of loss or mutation of SMN1. Although the SMN1 homolog SMN2 also produces some SMN protein, it d...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Harahap, Nur Imma Fatimah, Nurputra, Dian Kesumapramudya, Ar Rochmah, Mawaddah, Shima, Ai, Morisada, Naoya, Takarada, Toru, Takeuchi, Atsuko, Tohyama, Yumi, Yanagisawa, Shinichiro, Nishio, Hisahide
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669398/
https://ncbi.nlm.nih.gov/pubmed/29124224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.10.012
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