Cinnamaldehyde, Cinnamic Acid, and Cinnamyl Alcohol, the Bioactives of Cinnamomum cassia Exhibit HDAC8 Inhibitory Activity: An In vitro and In silico Study

BACKGROUND: The altered expression of histone deacetylase family member 8 (HDAC8) has been found to be linked with various cancers, thereby making its selective inhibition a potential strategy in cancer therapy. Recently, plant secondary metabolites, particularly phenolic compounds, have been shown...

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Détails bibliographiques
Publié dans:Pharmacogn Mag
Auteurs principaux: Patil, Mangesh, Choudhari, Amit S., Pandita, Savita, Islam, Md Ataul, Raina, Prerna, Kaul-Ghanekar, Ruchika
Format: Artigo
Langue:Inglês
Publié: Medknow Publications & Media Pvt Ltd 2017
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669110/
https://ncbi.nlm.nih.gov/pubmed/29142427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/pm.pm_389_16
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