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Chalepin: A Compound from Ruta angustifolia L. Pers Exhibits Cell Cycle Arrest at S phase, Suppresses Nuclear Factor-Kappa B (NF-κB) Pathway, Signal Transducer and Activation of Transcription 3 (STAT3) Phosphorylation and Extrinsic Apoptotic Pathway in Non-small Cell Lung Cancer Carcinoma (A549)

BACKGROUND: Plants have been a major source of inspiration in developing novel drug compounds in the treatment of various diseases that afflict human beings worldwide. Ruta angustifolia L. Pers known locally as Garuda has been conventionally used for various medicinal purposes such as in the treatme...

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Detalhes bibliográficos
Publicado no:Pharmacogn Mag
Main Authors: Richardson, Jaime Stella Moses, Aminudin, Norhaniza, Abd Malek, Sri Nurestri
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669087/
https://ncbi.nlm.nih.gov/pubmed/29142404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/pm.pm_13_17
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