Tissue-engineered smooth muscle cell and endothelial progenitor cell bi-level cell sheets prevent progression of cardiac dysfunction, microvascular dysfunction, and interstitial fibrosis in a rodent model of type 1 diabetes-induced cardiomyopathy

BACKGROUND: Diabetes mellitus is a risk factor for coronary artery disease and diabetic cardiomyopathy, and adversely impacts outcomes following coronary artery bypass grafting. Current treatments focus on macro-revascularization and neglect the microvascular disease typical of diabetes mellitus-ind...

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Détails bibliographiques
Publié dans:Cardiovasc Diabetol
Auteurs principaux: Kawamura, Masashi, Paulsen, Michael J., Goldstone, Andrew B., Shudo, Yasuhiro, Wang, Hanjay, Steele, Amanda N., Stapleton, Lyndsay M., Edwards, Bryan B., Eskandari, Anahita, Truong, Vi N., Jaatinen, Kevin J., Ingason, Arnar B., Miyagawa, Shigeru, Sawa, Yoshiki, Woo, Y. Joseph
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Original Investigation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668999/
https://ncbi.nlm.nih.gov/pubmed/29096622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-017-0625-4
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