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Folic acid prevents cardiac dysfunction and reduces myocardial fibrosis in a mouse model of high-fat diet-induced obesity

BACKGROUND: Folic acid (FA) is an antioxidant that can reduce reactive oxygen species generation and can blunt cardiac dysfunction during ischemia. We hypothesized that FA supplementation prevents cardiac fibrosis and cardiac dysfunction induced by obesity. METHODS: Six-week-old C57BL6/J mice were f...

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Detalhes bibliográficos
Publicado no:Nutr Metab (Lond)
Main Authors: Li, Wei, Tang, Renqiao, Ouyang, Shengrong, Ma, Feifei, Liu, Zhuo, Wu, Jianxin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668988/
https://ncbi.nlm.nih.gov/pubmed/29118818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-017-0224-0
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