HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient

Hi-C is a powerful technology for studying genome-wide chromatin interactions. However, current methods for assessing Hi-C data reproducibility can produce misleading results because they ignore spatial features in Hi-C data, such as domain structure and distance dependence. We present HiCRep, a fra...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Yang, Tao, Zhang, Feipeng, Yardımcı, Galip Gürkan, Song, Fan, Hardison, Ross C., Noble, William Stafford, Yue, Feng, Li, Qunhua
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668950/
https://ncbi.nlm.nih.gov/pubmed/28855260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.220640.117
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