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Greater transforming growth factor-β in adult female SHR is dependent on blood pressure, but does not account for sex differences in renal T-regulatory cells

Female spontaneously hypertensive rats (SHR) have more renal regulatory T cells (Tregs) than males, and greater levels of Tregs in female SHR are dependent on blood pressure (BP). However, the molecular mechanism responsible for greater Tregs in female SHR is unknown. Transforming growth factor (TGF...

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Pubblicato in:Am J Physiol Renal Physiol
Autori principali: Tipton, Ashlee J., Musall, Jacqueline B., Crislip, G. Ryan, Sullivan, Jennifer C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668580/
https://ncbi.nlm.nih.gov/pubmed/28679591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00175.2017
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