Identification of pharmacological agents that induce HMGB1 release

The translocation of the protein high mobility group box 1 (HMGB1) from the nucleus to the cytoplasm and its secretion or passive release through the permeabilized plasma membrane, constitutes a major cellular danger signal. Extracellular HMGB1 can interact with pattern recognition receptors to stim...

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Publicado en:Sci Rep
Autores principales: Liu, Peng, Zhao, Liwei, Loos, Friedemann, Iribarren, Kristina, Lachkar, Sylvie, Zhou, Heng, Gomes-da-Silva, Lígia C., Chen, Guo, Bezu, Lucillia, Boncompain, Gaelle, Perez, Franck, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668281/
https://ncbi.nlm.nih.gov/pubmed/29097772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14848-1
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