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Efficacy of an Adenoviral Vectored Multivalent Centralized Influenza Vaccine

Mice were immunized with Adenovirus expressing the H1-con, H2-con, H3-con and H5-con HA consensus genes in combination (multivalent) and compared to mice immunized with the traditional 2010–2011 FluZone and FluMist seasonal vaccines. Immunized mice were challenged with 10–100 MLD(50) of H1N1, H3N1,...

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Publicat a:Sci Rep
Autors principals: Lingel, Amy, Bullard, Brianna L., Weaver, Eric A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668234/
https://ncbi.nlm.nih.gov/pubmed/29097763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14891-y
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