Caveolae-Mediated Endocytosis is Critical for Albumin Cellular Uptake and Response to Albumin-Bound Chemotherapy

Nab-paclitaxel, a nanoparticle conjugate of paclitaxel to human albumin, exhibits efficacy in pancreatic cancer, non-small cell lung cancer and breast cancer. However, there is a lack of predictive biomarkers to identify patients who might benefit most from its administration. This study addresses t...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Chatterjee, Moumita, Ben-Josef, Edgar, Robb, Ryan, Vedaie, Marall, Seum, Star, Thirumoorthy, Krishnan, Palanichamy, Kamalakannan, Harbrecht, Matthew, Chakravarti, Arnab, Williams, Terence M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668166/
https://ncbi.nlm.nih.gov/pubmed/28923854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0604
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