Prediction of radio-responsiveness with immune-profiling in patients with rectal cancer

We evaluate whether the tumor immune infiltrate (TIL) could be used for prediction of responsiveness to preoperative chemoradiotherapy (PCRT) in rectal cancers. Using formalin-fixed paraffin-embedded slides of pretreatment biopsies, co-stain for CD4, CD8, CD274 (PD-L1), FOXP3, cytokeratin, and DAPI...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, In Ja, An, Soyeon, Kim, Sang-Yeob, Lim, Hye Min, Hong, Seung-Mo, Kim, Mi-Ju, Kim, Yun Jae, Yu, Chang Sik
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668093/
https://ncbi.nlm.nih.gov/pubmed/29108360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19558
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