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Non-radioactive 2-deoxy-2-fluoro-D-glucose inhibits glucose uptake in xenograft tumours and sensitizes HeLa cells to doxorubicin in vitro

A glucose analog called 2-deoxy-D-glucose (2DG) has been successfully used to sensitize cancer cells to ROS-inducing cancer treatments such as ionizing radiation, through the inhibition of glycolysis. However, the use of 2DG can be limited by several factors such as availability, non-specific cytoto...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Niccoli, Sarah, Boreham, Douglas R., Phenix, Christopher P., Lees, Simon J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667878/
https://ncbi.nlm.nih.gov/pubmed/29095925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187584
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