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Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients with myoadenylate deaminase deficiency

PURPOSE: Current evidence indicates that the common AMPD1 gene variant is associated with improved survival in patients with advanced heart failure. Whilst adenosine has been recognized to mediate the cardioprotective effect of C34T AMPD1, the precise pathophysiologic mechanism involved remains unde...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Rannou, Fabrice, Scotet, Virginie, Marcorelles, Pascale, Monnoyer, Roxane, Le Maréchal, Cédric
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667816/
https://ncbi.nlm.nih.gov/pubmed/29095874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187266
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