Crosstalk Between MLO‐Y4 Osteocytes and C2C12 Muscle Cells Is Mediated by the Wnt/β‐Catenin Pathway

We examined the effects of osteocyte secreted factors on myogenesis and muscle function. MLO‐Y4 osteocyte‐like cell conditioned media (CM) (10%) increased ex vivo soleus muscle contractile force by ∼25%. MLO‐Y4 and primary osteocyte CM (1% to 10%) stimulated myogenic differentiation of C2C12 myoblas...

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Detalhes bibliográficos
Publicado no:JBMR Plus
Main Authors: Huang, Jian, Romero‐Suarez, Sandra, Lara, Nuria, Mo, Chenglin, Kaja, Simon, Brotto, Leticia, Dallas, Sarah L, Johnson, Mark L, Jähn, Katharina, Bonewald, Lynda F, Brotto, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667655/
https://ncbi.nlm.nih.gov/pubmed/29104955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10015
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