Isolation and prolonged expansion of oral mesenchymal stem cells under clinical-grade, GMP-compliant conditions differentially affects “stemness” properties

BACKGROUND: Development of clinical-grade cell preparations is central to meeting the regulatory requirements for cellular therapies under good manufacturing practice-compliant (cGMP) conditions. Since addition of animal serum in culture media may compromise safe and efficient expansion of mesenchym...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Bakopoulou, Athina, Apatzidou, Danae, Aggelidou, Eleni, Gousopoulou, Evangelia, Leyhausen, Gabriele, Volk, Joachim, Kritis, Aristeidis, Koidis, Petros, Geurtsen, Werner
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667471/
https://ncbi.nlm.nih.gov/pubmed/29096714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0705-0
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