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Combination of ester biosynthesis and ω-oxidation for production of mono-ethyl dicarboxylic acids and di-ethyl esters in a whole-cell biocatalytic setup with Escherichia coli

BACKGROUND: Medium chain length (C6–C12) α,ω-dicarboxylic acids (DCAs) and corresponding esters are important building blocks for the polymer industry. For DCAs of 12 carbon atoms and longer, a sustainable process based on monooxygenase catalyzed ω-oxidation of fatty-acids has been realized. For med...

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: van Nuland, Youri M., Eggink, Gerrit, Weusthuis, Ruud A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667465/
https://ncbi.nlm.nih.gov/pubmed/29096635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0803-9
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