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Human iPSC-derived chondrocytes mimic juvenile chondrocyte function for the dual advantage of increased proliferation and resistance to IL-1β

BACKGROUND: Induced pluripotent stem cells (iPSC) provide an unlimited patient-specific cell source for regenerative medicine. Adult cells have had limited success in cartilage repair, but juvenile chondrocytes (from donors younger than 13 years of age) have been identified to generate superior cart...

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Bibliografske podrobnosti
izdano v:Stem Cell Res Ther
Main Authors: Lee, Jieun, Smeriglio, Piera, Chu, Constance R., Bhutani, Nidhi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667438/
https://ncbi.nlm.nih.gov/pubmed/29096706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0696-x
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