Decrease in Lymphoid Specific Helicase and 5-hydroxymethylcytosine Is Associated with Metastasis and Genome Instability

DNA methylation is an important epigenetic modification as a hallmark in cancer. Conversion of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) by ten-eleven translocation (TET) family enzymes plays an important biological role in embryonic stem cells, development, aging and disease. Lymph...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Jia, Jiantao, Shi, Ying, Chen, Ling, Lai, Weiwei, Yan, Bin, Jiang, Yiqun, Xiao, Desheng, Xi, Sichuan, Cao, Ya, Liu, Shuang, Cheng, Yan, Tao, Yongguang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667415/
https://ncbi.nlm.nih.gov/pubmed/29109788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21389
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