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Improved Tumor Targeting and Longer Retention Time of NIR Fluorescent Probes Using Bioorthogonal Chemistry

The traditional labeling method for targeted NIR fluorescence probes requires directly covalent-bonded conjugation of targeting domains and fluorophores in vitro. Although this strategy works well, it is not sufficient for detecting or treating cancers in vivo, due to steric hindrance effects that r...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhang, Xianghan, Wang, Bo, Zhao, Na, Tian, Zuhong, Dai, Yunpeng, Nie, Yongzhan, Tian, Jie, Wang, Zhongliang, Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667349/
https://ncbi.nlm.nih.gov/pubmed/29109777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.20912
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