Clinical trial protocol for TARDOX: a phase I study to investigate the feasibility of targeted release of lyso-thermosensitive liposomal doxorubicin (ThermoDox®) using focused ultrasound in patients with liver tumours

BACKGROUND: TARDOX is a Phase I single center study of ultrasound triggered targeted drug delivery in adult oncology patients with incurable liver tumours. This proof of concept study is designed to demonstrate the safety and feasibility of targeted drug release and enhanced delivery of doxorubicin...

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Detalhes bibliográficos
Publicado no:J Ther Ultrasound
Main Authors: Lyon, Paul C., Griffiths, Lucy F., Lee, Jenni, Chung, Daniel, Carlisle, Robert, Wu, Feng, Middleton, Mark R., Gleeson, Fergus V., Coussios, Constantin C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667032/
https://ncbi.nlm.nih.gov/pubmed/29118984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40349-017-0104-0
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