PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs

Poly (ADP-ribose) polymerase 1 (PARP1), the best-studied isoform of the nuclear enzyme PARP family, plays a pivotal role in cellular biological processes, such as DNA repair, gene transcription, and so on. PARP1 has been found to be overexpressed in various carcinomas. These all indicate the clinica...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Wang, Luyao, Liang, Chao, Li, Fangfei, Guan, Daogang, Wu, Xiaoqiu, Fu, Xuekun, Lu, Aiping, Zhang, Ge
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2017
Ämnen:
Review
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666793/
https://ncbi.nlm.nih.gov/pubmed/28991194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18102111
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