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Geranylgeranylacetone Ameliorates Intestinal Radiation Toxicity by Preventing Endothelial Cell Dysfunction

Radiation-induced intestinal toxicity is common among cancer patients after radiotherapy. Endothelial cell dysfunction is believed to be a critical contributor to radiation tissue injury in the intestine. Geranylgeranylacetone (GGA) has been used to treat peptic ulcers and gastritis. However, the pr...

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Pubblicato in:Int J Mol Sci
Autori principali: Han, Na-Kyung, Jeong, Ye Ji, Pyun, Bo-Jeong, Lee, Yoon-Jin, Kim, Sung-Ho, Lee, Hae-June
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666785/
https://ncbi.nlm.nih.gov/pubmed/28991157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18102103
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