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Skeletal Muscle-Specific Overexpression of PGC-1α Induces Fiber-Type Conversion through Enhanced Mitochondrial Respiration and Fatty Acid Oxidation in Mice and Pigs

Individual skeletal muscles in the animal body are heterogeneous, as each is comprised of different fiber types. Type I muscle fibers are rich with mitochondria, and have high oxidative metabolisms while type IIB fibers have few mitochondria and high glycolytic metabolic capacity. Peroxisome prolife...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Zhang, Lin, Zhou, Ying, Wu, Wangjun, Hou, Liming, Chen, Hongxing, Zuo, Bo, Xiong, Yuanzhu, Yang, Jinzeng
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666330/
https://ncbi.nlm.nih.gov/pubmed/29104506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.20132
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