A carregar...

Human microbiome signatures of differential colorectal cancer drug metabolism

It is well appreciated that microbial metabolism of drugs can influence treatment efficacy. Microbial β-glucuronidases in the gut can reactivate the excreted, inactive metabolite of irinotecan, a first-line chemotherapeutic for metastatic colorectal cancer. Reactivation causes adverse drug responses...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:NPJ Biofilms Microbiomes
Main Authors: Guthrie, Leah, Gupta, Sanchit, Daily, Johanna, Kelly, Libusha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665930/
https://ncbi.nlm.nih.gov/pubmed/29104759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41522-017-0034-1
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!