E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning

Generation of a barrier in multi-layered epithelia like the epidermis requires restricted positioning of functional tight junctions (TJ) to the most suprabasal viable layer. This positioning necessitates tissue-level polarization of junctions and the cytoskeleton through unknown mechanisms. Using qu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rübsam, Matthias, Mertz, Aaron F., Kubo, Akiharu, Marg, Susanna, Jüngst, Christian, Goranci-Buzhala, Gladiola, Schauss, Astrid C., Horsley, Valerie, Dufresne, Eric R., Moser, Markus, Ziegler, Wolfgang, Amagai, Masayuki, Wickström, Sara A., Niessen, Carien M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665913/
https://ncbi.nlm.nih.gov/pubmed/29093447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01170-7
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