Zika Virus Infects Intermediate Progenitor Cells and Post-mitotic Committed Neurons in Human Fetal Brain Tissues

Zika virus (ZIKV) infection is associated with microcephaly in fetuses, but the pathogenesis of ZIKV-related microcephaly is not well understood. Here we show that ZIKV infects the subventricular zone in human fetal brain tissues and that the tissue tropism broadens with the progression of gestation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lin, Ming-Yi, Wang, Yi-Ling, Wu, Wan-Lin, Wolseley, Victoria, Tsai, Ming-Ting, Radic, Vladimir, Thornton, Matthew E., Grubbs, Brendan H., Chow, Robert H., Huang, I-Chueh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665882/
https://ncbi.nlm.nih.gov/pubmed/29093521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13980-2
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