miR-16 and miR-103 impact 5-HT(4) receptor signalling and correlate with symptom profile in irritable bowel syndrome

Irritable bowel syndrome (IBS) is a gut-brain disorder involving alterations in intestinal sensitivity and motility. Serotonin 5-HT(4) receptors are promising candidates in IBS pathophysiology since they regulate gut motor function and stool consistency, and targeted 5-HT(4)R selective drug interven...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Sci Rep
المؤلفون الرئيسيون: Wohlfarth, Carolin, Schmitteckert, Stefanie, Härtle, Janina D., Houghton, Lesley A., Dweep, Harsh, Fortea, Marina, Assadi, Ghazaleh, Braun, Alexander, Mederer, Tanja, Pöhner, Sarina, Becker, Philip P., Fischer, Christine, Granzow, Martin, Mönnikes, Hubert, Mayer, Emeran A., Sayuk, Gregory, Boeckxstaens, Guy, Wouters, Mira M., Simrén, Magnus, Lindberg, Greger, Ohlsson, Bodil, Schmidt, Peter Thelin, Dlugosz, Aldona, Agreus, Lars, Andreasson, Anna, D’Amato, Mauro, Burwinkel, Barbara, Bermejo, Justo Lorenzo, Röth, Ralph, Lasitschka, Felix, Vicario, Maria, Metzger, Marco, Santos, Javier, Rappold, Gudrun A., Martinez, Cristina, Niesler, Beate
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group UK 2017
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665867/
https://ncbi.nlm.nih.gov/pubmed/29089619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13982-0
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