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Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function

Increased serum urate predicts chronic kidney disease independent of other risk factors. The use of xanthine oxidase inhibitors coincides with improved renal function. Whether this is due to reduced serum urate or reduced production of oxidants by xanthine oxidase or another physiological mechanism...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Kidney Int
मुख्य लेखकों: Hughes, Kim, Flynn, Tanya, de Zoysa, Janak, Dalbeth, Nicola, Merriman, Tony R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665684/
https://ncbi.nlm.nih.gov/pubmed/24048376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.353
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