Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation

Lipid droplet (LD) coating proteins are essential for the formation and stability of intracellular LDs. Plin2 is an abundant LD coating protein in skeletal muscle, but its importance for muscle function is unclear. We show that myotubes established from Plin2(−/−) mice contain reduced content of LDs...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Feng, Yuan Z., Lund, Jenny, Li, Yuchuan, Knabenes, Irlin K., Bakke, Siril S., Kase, Eili T., Lee, Yun K., Kimmel, Alan R., Thoresen, G. Hege, Rustan, Arild Christian, Dalen, Knut Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665670/
https://ncbi.nlm.nih.gov/pubmed/28822960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079764
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