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Effects of hyperoxia on (18)F-fluoro-misonidazole brain uptake and tissue oxygen tension following middle cerebral artery occlusion in rodents: Pilot studies

PURPOSE: Mapping brain hypoxia is a major goal for stroke diagnosis, pathophysiology and treatment monitoring. (18)F-fluoro-misonidazole (FMISO) positron emission tomography (PET) is the gold standard hypoxia imaging method. Normobaric hyperoxia (NBO) is a promising therapy in acute stroke. In this...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fryer, Tim D., Ejaz, Sohail, Jensen-Kondering, Ulf, Williamson, David J., Sitnikov, Sergey, Sawiak, Stephen J., Aigbirhio, Franklin I., Hong, Young T., Baron, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665507/
https://ncbi.nlm.nih.gov/pubmed/29091934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187087
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