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MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy

Levels of matrix metalloproteases (MMPs) can be differentially regulated in response to injury or neurological diseases. For instance, it is known that selective and short-term inhibition of MMP-14, a membrane-type 1 MMP, accelerates axon regeneration. Because axon growth and regeneration is impaire...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Martins, Diana, Moreira, João, Gonçalves, Nádia Pereira, Saraiva, Maria João
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665453/
https://ncbi.nlm.nih.gov/pubmed/28993312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.028571
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