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LPP3 mediates self-generation of chemotactic LPA gradients by melanoma cells
Melanoma cells steer out of tumours using self-generated lysophosphatidic acid (LPA) gradients. The cells break down LPA, which is present at high levels around the tumours, creating a dynamic gradient that is low in the tumour and high outside. They then migrate up this gradient, creating a complex...
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| Опубликовано в: : | J Cell Sci |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists Ltd
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5665449/ https://ncbi.nlm.nih.gov/pubmed/28871044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.207514 |
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