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PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody

Tumor antigen-targeting monoclonal antibodies (TA-targeting mAbs) are used as therapeutics in many malignancies and their capacity to mobilize the host immunity puts them at the forefront of anti-cancer immunotherapies. Both innate and adaptive immune cells have been associated with the therapeutic...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: They, Laetitia, Michaud, Henri-Alexandre, Becquart, Ondine, Lafont, Virginie, Guillot, Bernard, Boissière-Michot, Florence, Jarlier, Marta, Mollevi, Caroline, Eliaou, Jean-François, Bonnefoy, Nathalie, Gros, Laurent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665071/
https://ncbi.nlm.nih.gov/pubmed/29123966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1353857
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