FH535 Inhibits Proliferation and Motility of Colon Cancer Cells by Targeting Wnt/β-catenin Signaling Pathway

Aberrant Wnt/β-catenin pathway activation is frequently observed in human colorectal cancer (CRC) and has become a promising target for CRC treatment. Our study aimed to evaluate the effect of FH535, a small molecule inhibitor of Wnt/β-catenin pathway, on two colon cancer cell lines, HT29 and SW480....

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Chen, Yanyan, Rao, Xianping, Huang, Kangmao, Jiang, Xiaoxia, Wang, Haohao, Teng, Lisong
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665030/
https://ncbi.nlm.nih.gov/pubmed/29158786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19273
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