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Induction of anti-Ro60/anti-La by immunization with spectrin and, induction of anti-spectrin by immunization with Ro60 and 4-hydroxy-2-nonenal-modified Ro60 immunization

INTRODUCTION: The Ro ribonucleoprotein particle, targeted in systemic lupus erythematosus (SLE) and Sjögren’s syndrome (SS), includes Ro60 (SSA) and La (SSA) autoantigen. Anti-Ro60 occurs in SLE and SS. The importance of α-fodrin and spectrin as well as anti-Ro and anti-fodrin/spectrin antibodies in...

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Detalhes bibliográficos
Publicado no:Clin Exp Rheumatol
Main Authors: Kurien, Biji T., Dorri, Yaser, Bachmann, Michael, Scofield, R. Hal
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664947/
https://ncbi.nlm.nih.gov/pubmed/22776429
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