FGF4 retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs

Chondrodystrophy in dogs is defined by dysplastic, shortened long bones and premature degeneration and calcification of intervertebral discs. Independent genome-wide association analyses for skeletal dysplasia (short limbs) within a single breed (P(Bonferroni) = 0.01) and intervertebral disc disease...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Brown, Emily A., Dickinson, Peter J., Mansour, Tamer, Sturges, Beverly K., Aguilar, Miriam, Young, Amy E., Korff, Courtney, Lind, Jenna, Ettinger, Cassandra L., Varon, Samuel, Pollard, Rachel, Brown, C. Titus, Raudsepp, Terje, Bannasch, Danika L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664524/
https://ncbi.nlm.nih.gov/pubmed/29073074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1709082114
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