Development and Characterization of Cholangioids from Normal and Diseased Human Cholangiocytes as an In Vitro Model to Study Primary Sclerosing Cholangitis

Primary sclerosing cholangitis (PSC) is an incurable, fibroinflammatory biliary disease for which there is no effective pharmacotherapy. We recently reported cholangiocyte senescence as an important phenotype in PSC while others showed that portal macrophages accumulate in PSC. Unfortunately, our ab...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Loarca, Lorena, De Assuncao, Thiago M., Jalan-Sakrikar, Nidhi, Bronk, Steve, Krishan, Anuradha, Huang, Bing, Morton, Leslie, Trussoni, Christy, Bonilla, Lorena Marcano, Krueger, Eugene, O’Hara, Steve, Splinter, Patrick, Shi, Guang, Pisarello, María José Lorenzo, Gores, Gregory J., Huebert, Robert C., LaRusso, Nicholas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664217/
https://ncbi.nlm.nih.gov/pubmed/28892096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2017.63
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