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Transcription instability in high‐risk neuroblastoma is associated with a global perturbation of chromatin domains

Chromosome instability has a pivotal role among the hallmarks of cancer, but its transcriptional counterpart is rarely considered a relevant factor in cell destabilization. To examine transcription instability (TIN), we first devised a metric we named TIN index and used it to evaluate TIN on a datas...

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Библиографические подробности
Опубликовано в: :Mol Oncol
Главные авторы: Zanon, Carlo, Tonini, Gian Paolo
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664000/
https://ncbi.nlm.nih.gov/pubmed/28941026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12139
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