Splice variants of cytosolic polyadenylation element–binding protein 2 (CPEB2) differentially regulate pathways linked to cancer metastasis

The translational regulator cytosolic polyadenylation element–binding protein 2 (CPEB2) has two isoforms, CPEB2A and CPEB2B, derived by alternative splicing of RNA into a mature form that either includes or excludes exon 4. Previously, we reported that this splicing event is highly dysregulated in a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: DeLigio, James T., Lin, Grace, Chalfant, Charles E., Park, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663888/
https://ncbi.nlm.nih.gov/pubmed/28904175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.810127
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