Downregulation of miR-199a-5p promotes prostate adeno-carcinoma progression through loss of its inhibition of HIF-1α

Hypoxia-inducible factor-1 alpha (HIF-1α) plays key roles in cell survival under both hypoxia and normoxia conditions. Regulation of HIF-1α is complex and involves numerous molecules and pathways, including post-transcriptional regulation by microRNAs (miRNAs). Although upregulation of HIF-1α has be...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhong, Jinjing, Huang, Rui, Su, Zhengzheng, Zhang, Mengni, Xu, Miao, Gong, Jing, Chen, Ni, Zeng, Hao, Chen, Xueqin, Zhou, Qiao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663533/
https://ncbi.nlm.nih.gov/pubmed/29137361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18315
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