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Microfluidics Enabled Bottom-Up Engineering of 3D Vascularized Tumor for Drug Discovery

Development of high-fidelity 3D models to recapitulate the tumor microenvironment is essential for studying tumor biology and discovering anticancer drugs. Here we report a method to engineer the 3D microenvironment of human tumor, by encapsulating cancer cells in the core of microcapsules with a hy...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Agarwal, Pranay, Wang, Hai, Sun, Mingrui, Xu, Jiangsheng, Zhao, Shuting, Liu, Zhenguo, Gooch, Keith J., Zhao, Yi, Lu, Xiongbin, He, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663446/
https://ncbi.nlm.nih.gov/pubmed/28614653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b00824
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